We have studied in detail the process of obtaining a spherical powder of titanium Grade 5 alloy using inductively coupled argon-helium plasma from the initial powder of the fragmentation form. The mode of spheroidization process was worked out, and a spherical titanium alloy powder with a high percentage of yield suitable for additive technologies was obtained as a result. The structure of the titanium alloy was studied in detail before and after the spheroidization process. The results of granulometric and X-ray diffraction analysis were also obtained. As a result of analysis of the structure, a conclusion was made about the change in the size of crystallites and the magnitude of microstresses, the parameters of the unit cell were calculated, as well as its volume before and after spheroidization of the given alloy. The values of crystallite sizes and microstresses in the alloy were calculated.