The article presents ways and methods of using gas-filled relaxation systems to ensure safe use of pulsed high-energy technologies. The acoustic characteristics of relaxation systems, the expected limits of the pressure drop during the reflection of shock waves on a rigid wall in two-phase media are considered. The real possibilities of controlling the parameters of explosive waves during detonation of explosive charges in various media, the dynamic behavior of shock waves in relaxation systems are described. Various schemes and methods for converting underwater explosive loads are shown. Examples of using structured relaxation systems to protect against external, vibrational and vibrational influences are given. The relevance of describing the laws of evolution of shock-wave processes in gases, liquids and gas-liquid systems from a single perspective and identifying criteria for similarity of interaction of shock waves with biological objects and structures is given.