The influence of continuous mill 2000 hot rolling parameters on the high strength pipeline steel structure evolution was investigated. Computer simulation of structure and mechanical properties formation was realized with the help of Hot Strip Mill Model (HSMM), AusEvol + and AusTran programs. Physical simulation of metal thermomechanical treatment was made by Gleeble-3800. Found modes are provided to receipt mechanical properties that meet ISO requirements for the X80 strength class pipeline steels.