We have described a model of automation of technological preparation of production in single-unit and small-batch manufacturing. The model described allows to estimate the optimal technical route for processing a batch of components, production time, variable costs, optimal technological parameters of processing, to form a nomenclature and the number of necessary means of production, to manage warehouse stocks. Simulation is performed based on mathematical models for warehouse stock management (a combined model) and for determining the value of variable costs and the standard operational time. The definition of optimal variance is based on multicriteria analysis using the method of ideal point by three parameters: amount of variable costs, production time and duration of production.